Response and Adaptation to Chemicals in the Marine Environment

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Mark Hahn

We seek to understand how marine animals (primarily fish) respond to natural or anthropogenic chemicals in their environment. We use biochemical, genomic, and transcriptomic approaches in model species such as the Atlantic killifish (Fundulus heteroclitus) and zebrafish (Danio rerio) to understand the mechanisms underlying chemical effects, and how chemical exposure during sensitive developmental stages affects gene expression and can lead to effects later in life. We also study how some fish can adapt to long-term (multi-generational) exposure to chemicals. Several potential summer projects are possible within the context of ongoing projects (see web site). Examples include: 1) using recently generated mutant lines of fish (killifish or zebrafish) to study the role of specific transcription factors in chemical sensitivity, 2) studying the long-term behavioral effects of early life exposure to harmful algal bloom (HAB) toxins, 3) investigating the interactive effects chemicals and other environmental stressors such as hypoxia (low oxygen) on fish embryonic development.

Mark Hahn's Lab