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"Determining the Resistance of Marine Animals to Environmental Chemicals"

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Dr. Mark Hahn, WHOI, Biology Department
Dr. Hahn’s major research interests include receptor-mediated mechanisms of toxicity, and means of adaptation and acquired resistance to exposure to persistent organic pollutants. This presentation centered on looking at toxins in the marine environment, particularly dioxins, PCBs, POPs: the mechanisms of toxicity, what makes animals resistant, genetic markers for resistance.

Web-based Resources

Mark Hahn's web site
http://www.whoi.edu/science/B/people/mhahn/hahnm.html

NPR report on dioxin-resistant killifish from New Bedford Harbor
http://www.wgbh.org/cainan/article?item_id=530429

Dioxins-R-Us (general information and web sites on dioxin research)
http://dioxins-r-us.ucdavis.edu/TCDD

Dioxin information
http://www.ejnet.org/dioxin/

Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) Final Report
http://www.epa.gov/scipoly/oscpendo/history/finalrpt.htm

Fooling with Nature (PBS Frontline)
http://www.pbs.org/wgbh/pages/frontline/shows/nature/

Tulane University Center for Bioenvironmental Research
http://www.cbr.tulane.edu/

Chlorine Chemistry Council
http://www.c3.org/teacher_education_materials/index.html

EPA Endocrine Disruptor Screening Program web site
http://www.epa.gov/oscpmont/oscpendo/index.html

National Institute of Environmental Health Sciences, endocrine disruptors
http://www.niehs.nih.gov/external/faq/alpha.htm

Marine Environmental Research Institute (MERI)
http://www.meriresearch.org/

Silent Spring Institute
http://www.silentspring.org/

EPA Superfund Cleanup (for students)
http://www.epa.gov/superfund/students/clas_act/haz-ed/hazindex.htm

Endocrine Disruption in Wildlife Populations, by Woods Hole Sea Grant
http://www.whoi.edu/seagrant/education/focalpoints/endocrine.html

Research Update: Contaminants in the Marine Environmnet and their Effects on Marine Mammals, by Woods Hole Sea Grant
http://www.whoi.edu/seagrant/education/focalpoints/mammals.html

The Link Between Environmental Contaminants and Animal Susceptibility
Crago, T.I.
In: Two if by Sea, Vol. 4, No. 1, 2 pp.
Available online: http://web.mit.edu/seagrant/2ifbysea/issues/spring00/contaminants.html

Nor'easter Researcher Profile: Using Biomarkers to Detect Contamination of the Marine Environment
Hahn, M.E.
In: Nor'easter, Vol. 6, No. 1, pp. 8-11 Spring/Summer 1994

Evolution of Pathways for Chemical Sensing, Response, & Adaptation
Hahn, M.E.
In: Woods Hole Oceanographic Institution 1998 Annual Report, 2 pp.

Dioxin Toxicology and the Aryl Hydrocarbon Receptor: Insights from Fish and Other Non-traditional Models
Hahn, M.E.
In: Mar. Biotechnol., Vol. 3, pp. S224-S238 2001

Formation of a Biological Company, from Access Excellence @ the National Health Museum
http://www.accessexcellence.org/AE/ATG/data/released/0329-MiriamTurner/index.html

Survival in the Sea, from Secrets of the Ocean Realm
http://www.pbs.org/oceanrealm/intheschool/school2.html

Serial Dilutuion & PPM (activity), from the Advanced Technology Environmental Education Center
http://www.ateec.org/curric/activities/ac3.html

We All Live Downstream (activity), from Access Excellence @ the National Health Museum
http://www.accessexcellence.org/AE/ATG/data/released/0497-AlondaDroege/index.html

Acquired Resistance to Ah Receptor Agonists in a Population of Atlantic Killifish (Fundulus heteroclitus) Inhabiting a Marine Superfund Site: In Vivo and In Vitro Studies on the Inducibility of Xenobiotic Metabolizing Enzymes
Bello, S.M., D.G. Franks, J.J. Stegeman, and M.E. Hahn
In: Toxicological Sciences, Vol. 66, pp. 77-79 2001

cDNA Cloning and Characterization of a High Affinity Aryl Hydrocarbon Receptor in a Cetacean, the Beluga, Delphinapterus leucas
Jensen, B.A. and M.E. Hahn
In: Toxicological Sciences, Vol. 64, pp. 45-56 2001

cDNA Cloning and Characterization of an Aryl Hydrocarbon Receptor from the Harbor Seal (Phoca vitulina): A Biomarker of Dioxin Susceptibility?
Kim, E.-Y. and M.E. Hahn
In: Aquat. Toxicol., Vol. 58, pp. 57-73 2002



Last updated: June 24, 2014
 


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