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You are here: WHCOHH Frontpage > Genomic Core Facility: History

Genomic Core Facility: History

Instrumentation

Dual 384-well block thermocyclers Dual 384-well block thermocyclers for cycle-sequencing reactions.


MWGBiotech RoboPrep2500 MWGBiotech RoboPrep2500, used to generate transfection-quality plasmid DNA using solid-phase binding methods.


GenomicSolutions Omnigrid microarrayer GenomicSolutions Omnigrid microarrayer.
DNA sequencing in the Josephine Bay Paul Center for Comparative Molecular Biology and Evolution

Over the past decade, scientists in the Woods Hole community have adapted molecular biology and high-throughput DNA sequencing technologies to address important questions about parasitology, microbial diversity, genome evolution, molecular evolution, and ecology. These research initiatives capitalized on early investments in DNA sequencing in the Josephine Bay Paul Center for Comparative Molecular Biology and Evolution (JBPC) at the Marine Biological Laboratory (MBL) in Woods Hole.

Our DNA sequencing and associated robotic technology has supported genome projects for parasitic protists, Serial Analysis of Gene Expression (SAGE) projects for Giardia lamblia, Emiliania huxleyi and several Trypanosoma species, NASA-sponsored metagenomic and large-scale molecular microbial population structure studies, and NSF-sponsored LEXEN and Microbial Observatory Programs at Plum Island and Costa Rica.

There is a clear trend towards higher levels of DNA sequencing activity in the Woods Hole scientific community.