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Possible influence of bacterial quorum sensing on the hydrolysis of sinking particulate organic carbon in marine environments
Quorum sensing control of phosphorus acquisition in Trichodesmium consortia.
Composition and fate of gas and oil released to the water column during the Deepwater Horizon spill.
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Bacterial and eukaryotic intact polar lipids in the eastern subtropical South Pacific: water-column distribution, planktonic sources, and fatty acid composition.
Abundance and diversity of heterotrophic bacterial cells assimilating 33P-phosphate in the subtropical North Atlantic Ocean
Tracking hydrocarbon plume transport and biodegradation at Deepwater Horizon
Viral glycosphingolipids induce lytic infection and cell death in marine phytoplankton
Kinetic constraints on acylated homoserine lactone-based quorum sensing in marine environments
Phytoplankton in the ocean substitute lipids in response to phosphorus scarcity
An interlaboratory study of TEX86 and BIT analysis using high-performance liquid chromatography-mass spectrometry
Assessing nutrient limitation of Prochlorococcus in the North Pacific subtropical gyre by using an RNA capture method
Phospholipid synthesis rates in the eastern subtropical South Pacific Ocean
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Primary, new and export production in the NW Pacific Subarctic Gyre during the VERTIGO K2 experiments
Microbial vs. zooplankton control of sinking particle flux in the ocean's twilight zone
Phosphate availability: ultimate control of new nitrogen input by nitrogen fixation in the tropical Pacific Ocean
Growth and P-specific uptake rates of bacterial and phytoplanktonic communities in the Southeast Pacific (BISOSOPE cruise)
Microbes and the marine phosphorus cycle.
Revisiting carbon flux through the ocean's twilight zone.
Sulfolipids dramatically decrease phosphorus demand by picocyanobacteria in oligotrophic marine environments.
Quantifying 3H-thymidine incorporation rates by a phylogenetically defined group of marine planktonic bacteria (Bacteriodetes phylum).
Relationships between bacterial community structure, light, and carbon cycling in the eastern subarctic North Pacific
Impact of suboxia on sinking particulate organic carbon: Enhanced carbon flux and preferential degradation of amino acids via denitrification
Seasonal variation in sedimentary amino acids and the association of organic matter with mineral surfaces in a sandy eelgrass meadow
Evidence of tight coupling between bacteria and particulate organic carbon during seasonal stratification of Lake Michigan.
Microbiological, molecular biological and stable isotope evidence for nitrogen fixation in the open waters of Lake Michigan
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Viral glycosphingolipids induce lytic infection and cell death in marine phytoplankton

Vardi A., Van Mooy B. A. S., *Fredricks H. F., *Popendorf K. J., *Ossolinski J. E., Haramaty L., and Bidle K. A.

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Production of viral GSLs in EhV86-infected E. huxleyi cells and in purified EhV86 virions. Summed ion HPLC/MS chromatograms showing relative abundances (normalized to an internal standard) of GSLs extracted from (A) susceptible Ehux374, (B) Ehux374 infected with EhV86 52 hours post infection, (C) purified EhV86 on a CsCl2 gradient, and (D) resistant Ehux373 infected with EhV86 52 hours post infection. (Insets) TEM micrographs of respective treatments. Arrows in (B) depict intracytoplasmic vacuoles (C) that contain viral particles (V).


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» Full text of article can be found here.

Science 326, 861-865. (2009)


Abstract
Marine viruses that infect phytoplankton are recognized as a major ecological and evolutionary driving force, shaping community structure and nutrient cycling in the marine environment. Little is known about the signal transduction pathways mediating viral infection. We show that viral glycosphingolipids regulate infection of Emiliania huxleyi, a cosmopolitan coccolithophore that plays a major role in the global carbon cycle. These sphingolipids derive from an unprecedented cluster of biosynthetic genes in Coccolithovirus genomes, are synthesized de novo during lytic infection, and are enriched in virion membranes. Purified glycosphingolipids induced biochemical hallmarks of programmed cell death in an uninfected host. These lipids were detected in coccolithophore populations in the North Atlantic, which highlights their potential as biomarkers for viral infection in the oceans.

Last updated: December 14, 2011
 


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